"Nunca he abierto el juego con el peón de mi reina."

Simplified Meaning:

The person speaking has a preferred way of starting a game of chess and has never tried other approaches, specifically using the "queen's pawn." Just like in chess, people often stick to certain routines or methods they are comfortable with. For example, imagine someone who always drives the same route to work every day because they know it well and feel safe with it. They might like this routine and not want to try an unfamiliar road. This quote suggests the importance of comfort in familiar strategies but also implies that the person hasn't explored other potentially successful options. In life, trying new things can sometimes lead to better results or new experiences. So, if you're used to a specific way of doing things, it might be beneficial to occasionally try something different; it could bring positive changes or improvements.